Hepatic mitochondrial dysfunction in Friedreich Ataxia

BACKGROUND: Mitochondrial dysfunction due to respiratory chain impairment is a key feature in pathogenesis of Friedreich ataxia. Friedreich ataxia affects the nervous system, heart and pancreas. METHODS: We assessed hepatic mitochondrial function by (13)C-methionine-breath-test in 16 Friedreich atax...

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Main Authors: Stüwe, Sven H, Goetze, Oliver, Arning, Larissa, Banasch, Matthias, Schmidt, Wolfgang E, Schöls, Ludger, Saft, Carsten
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226643/
https://ncbi.nlm.nih.gov/pubmed/22085827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-11-145
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