CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease

BACKGROUND: Increasing evidence suggests that microglial activation may participate in the aetiology and pathogenesis of Parkinson's disease (PD). CD200-CD200R signalling has been shown to be critical for restraining microglial activation. We have previously shown that expression of CD200R in m...

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Detalhes bibliográficos
Main Authors: Zhang, Shi, Wang, Xi-Jin, Tian, Li-Peng, Pan, Jing, Lu, Guo-Qiang, Zhang, Ying-Jie, Ding, Jian-Qing, Chen, Sheng-Di
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226566/
https://ncbi.nlm.nih.gov/pubmed/22053982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-154
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