Electrostatically Biased Binding of Kinesin to Microtubules

The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the progress direction of the motor. A specific molecu...

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Главные авторы: Grant, Barry J., M. Gheorghe, Dana, Zheng, Wenjun, Alonso, Maria, Huber, Gary, Dlugosz, Maciej, McCammon, J. Andrew, Cross, Robert A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226556/
https://ncbi.nlm.nih.gov/pubmed/22140358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001207
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