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Electrostatic steering enhances the rate of cAMP binding to phosphodiesterase: Brownian dynamics modeling
Signaling in cells often involves co-localization of the signaling molecules. Most experimental evidence has shown that intracellular compartmentalization restricts the range of action of the second messenger, 3'-5'-cyclic adenosine monophosphate (cAMP), which is degraded by phosphodiester...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622220/ https://ncbi.nlm.nih.gov/pubmed/26346301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2794 |
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