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Development of a Nongenetic Mouse Model of Type 2 Diabetes

Insulin resistance and loss of β-cell mass cause Type 2 diabetes (T2D). The objective of this study was to generate a nongenetic mouse model of T2D. Ninety-six 6-month-old C57BL/6N males were assigned to 1 of 12 groups including (1) low-fat diet (LFD; low-fat control; LFC), (2) LFD with 1 i.p. 40 mg...

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Main Authors: Gilbert, Elizabeth R., Fu, Zhuo, Liu, Dongmin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226533/
https://ncbi.nlm.nih.gov/pubmed/22164157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/416254
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