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Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

Type 2 diabetes (T2D) is a growing health problem worldwide. While peripheral insulin resistance is common during obesity and aging in both animals and people, progression to T2D is largely due to insulin secretory dysfunction and significant apoptosis of functional β-cells, leading to an inability...

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Autori principali: Gilbert, Elizabeth R., Liu, Dongmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427279/
https://ncbi.nlm.nih.gov/pubmed/22810088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21238
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