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Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

Type 2 diabetes (T2D) is a growing health problem worldwide. While peripheral insulin resistance is common during obesity and aging in both animals and people, progression to T2D is largely due to insulin secretory dysfunction and significant apoptosis of functional β-cells, leading to an inability...

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Bibliografiske detaljer
Main Authors: Gilbert, Elizabeth R., Liu, Dongmin
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427279/
https://ncbi.nlm.nih.gov/pubmed/22810088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21238
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