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Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes
Type 2 diabetes (T2D) is a growing health problem worldwide. While peripheral insulin resistance is common during obesity and aging in both animals and people, progression to T2D is largely due to insulin secretory dysfunction and significant apoptosis of functional β-cells, leading to an inability...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427279/ https://ncbi.nlm.nih.gov/pubmed/22810088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21238 |
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