Selective targeted delivery of the TNF-alpha receptor p75 and uteroglobin to the vasculature of inflamed tissues: a preliminary report

BACKGROUND: Ligand-targeted approaches have proven successful in improving the therapeutic index of a number of drugs. We hypothesized that the specific targeting of TNF-alpha antagonists to inflamed tissues could increase drug efficacy and reduce side effects. RESULTS: Using uteroglobin (UG), a pot...

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Hauptverfasser: Ventura, Elisa, Balza, Enrica, Borsi, Laura, Tutolo, Giorgia, Carnemolla, Barbara, Castellani, Patrizia, Zardi, Luciano
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226451/
https://ncbi.nlm.nih.gov/pubmed/22074550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-104
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