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Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells

BACKGROUND: A proposed role for Myc in maintaining mouse embryonic stem (ES) cell pluripotency is transcriptional repression of key differentiation-promoting genes, but detail of the mechanism has remained an important open topic. RESULTS: To test the hypothesis that the zinc finger protein Miz-1 pl...

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Hlavní autoři: Varlakhanova, Natalia, Cotterman, Rebecca, Bradnam, Keith, Korf, Ian, Knoepfler, Paul S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226433/
https://ncbi.nlm.nih.gov/pubmed/22053792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-20
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