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Modeling Diabetes Disease Progression and Salsalate Intervention in Goto-Kakizaki Rats

Type 2 diabetes mellitus (T2DM) arises owing to insulin resistance and β-cell dysfunction. Chronic inflammation is widely identified as a cause of T2DM. The Goto-Kakizaki (GK) rat is a spontaneous rodent model for T2DM with chronic inflammation. The purpose of this study was to characterize diabetes...

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Hlavní autoři: Cao, Yanguang, DuBois, Debra C., Sun, Hao, Almon, Richard R., Jusko, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226370/
https://ncbi.nlm.nih.gov/pubmed/21903749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185686
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