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Impact of Pyrrolidine Dithiocarbamate and Interleukin-6 on Mammalian Target of Rapamycin Complex 1 Regulation and Global Protein Translation

Interleukin-6 (IL-6) is a proinflammatory cytokine that exerts a wide range of cellular, physiological, and pathophysiological responses. Pyrrolidine dithiocarbamate (PDTC) antagonizes the cellular responsiveness to IL-6 through impairment in signal transducer and activator of transcription-3 activa...

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Bibliografski detalji
Glavni autori: Song, Shaoming, Abdelmohsen, Kotb, Zhang, Yongqing, Becker, Kevin G., Gorospe, Myriam, Bernier, Michel
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226362/
https://ncbi.nlm.nih.gov/pubmed/21917559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185678
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