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Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3

Adaptive responses to physical and inflammatory stressors are mediated by transcription factors and molecular chaperones. The transcription factor heat shock factor 1 (HSF1) has been implicated in extending lifespan in part by increasing expression of heat shock response genes. Pyrrolidine dithiocar...

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Dettagli Bibliografici
Autori principali: Song, Shaoming, Kole, Sutapa, Precht, Patricia, Pazin, Michael J., Bernier, Michel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950225/
https://ncbi.nlm.nih.gov/pubmed/20692357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.07.021
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