Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial

INTRODUCTION: Neuroinflammation is thought to be important in Alzheimer's disease pathogenesis. Mast cells are a key component of the inflammatory network and participate in the regulation of the blood-brain barrier's permeability. Masitinib, a selective oral tyrosine kinase inhibitor, eff...

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Main Authors: Piette, François, Belmin, Joël, Vincent, Hélène, Schmidt, Nicolas, Pariel, Sylvie, Verny, Marc, Marquis, Caroline, Mely, Jean, Hugonot-Diener, Laurence, Kinet, Jean-Pierre, Dubreuil, Patrice, Moussy, Alain, Hermine, Olivier
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226277/
https://ncbi.nlm.nih.gov/pubmed/21504563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt75
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