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Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT
BACKGROUND: The stem cell factor receptor, KIT, is a target for the treatment of cancer, mastocytosis, and inflammatory diseases. Here, we characterise the in vitro and in vivo profiles of masitinib (AB1010), a novel phenylaminothiazole-type tyrosine kinase inhibitor that targets KIT. METHODOLOGY/PR...
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| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746281/ https://ncbi.nlm.nih.gov/pubmed/19789626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007258 |
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