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CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques

INTRODUCTION: APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and CR1 involved in Aβ clearance, and PICALM affecting intracellular trafficking. METHODS: We investigated the associations of...

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Autors principals: Kok, Eloise H, Luoto, Teemu, Haikonen, Satu, Goebeler, Sirkka, Haapasalo, Hannu, Karhunen, Pekka J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226274/
https://ncbi.nlm.nih.gov/pubmed/21466683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt71
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