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CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques
INTRODUCTION: APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and CR1 involved in Aβ clearance, and PICALM affecting intracellular trafficking. METHODS: We investigated the associations of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226274/ https://ncbi.nlm.nih.gov/pubmed/21466683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt71 |
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