Microcirculatory alterations in ischemia–reperfusion injury and sepsis: effects of activated protein C and thrombin inhibition

Experimental studies in ischemia–reperfusion and sepsis indicate that activated protein C (APC) has direct anti-inflammatory effects at a cellular level. In vivo, however, the mechanisms of action have not been characterized thus far. Intravital multifluorescence microscopy represents an elegant way...

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Hlavní autoři: Hoffmann, Johannes N, Vollmar, Brigitte, Laschke, Matthias W, Fertmann, Jan M, Jauch, Karl-Walter, Menger, Michael D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226166/
https://ncbi.nlm.nih.gov/pubmed/16168073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc3758
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