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The effect of an NADH oxidase inhibitor (hydrocortisone) on polymorphonuclear leukocyte bactericidal activity

Polymorphonuclear neutrophils (PMN) from patients with chronic granulomatous disease of childhood have impaired bactericidal activity and are deficient in diphosphopyridine nucleotide, reduced form of, (NADH) oxidase. Since hydrocortisone had been shown to inhibit NADH oxidation, experiments were un...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Mandell, Gerald L., Rubin, Walter, Hook, Edward W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1970
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4393490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106355
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