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The effect of an NADH oxidase inhibitor (hydrocortisone) on polymorphonuclear leukocyte bactericidal activity

Polymorphonuclear neutrophils (PMN) from patients with chronic granulomatous disease of childhood have impaired bactericidal activity and are deficient in diphosphopyridine nucleotide, reduced form of, (NADH) oxidase. Since hydrocortisone had been shown to inhibit NADH oxidation, experiments were un...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mandell, Gerald L., Rubin, Walter, Hook, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4393490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106355
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