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Transmission of prions within the gut and toward the central nervous system

The prion protein is a glycoprotein characterized by a folded α-helical structure that, under pathological conditions, misfolds and aggregates into its infectious isoform as β-sheet rich amyloidic deposits. The accumulation of the abnormal protein is responsible for a group of progressive and fatal...

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Bibliografske podrobnosti
Main Authors: Natale, Gianfranco, Ferrucci, Michela, Lazzeri, Gloria, Paparelli, Antonio, Fornai, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226038/
https://ncbi.nlm.nih.gov/pubmed/21814041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.3.16328
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