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Ubiquitination: Added complexity in Ras and Rho family GTPase function
The regulation of the small GTPases leading to their membrane localization has long been attributed to processing of their C-terminal CAAX box. As deregulation of many of these GTPases have been implicated in cancer and other disorders, prenylation and methylation of this CAAX box has been studied i...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225908/ https://ncbi.nlm.nih.gov/pubmed/22145091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.4.16707 |
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