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Ubiquitination: Added complexity in Ras and Rho family GTPase function

The regulation of the small GTPases leading to their membrane localization has long been attributed to processing of their C-terminal CAAX box. As deregulation of many of these GTPases have been implicated in cancer and other disorders, prenylation and methylation of this CAAX box has been studied i...

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Detalhes bibliográficos
Main Authors: de la Vega, Michelle, Burrows, James F, Johnston, James A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225908/
https://ncbi.nlm.nih.gov/pubmed/22145091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.4.16707
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