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Human leptin tissue distribution, but not weight loss-dependent change in expression, is associated with methylation of its promoter
Leptin is a master regulator of energy homeostasis. Its expression, prevalently localized in adipocytes, is positively related to adipose mass. Epigenetics is emerging as an important contributor to the changes in gene expression undergone by adipose tissue during obesity. We herein investigated the...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225841/ https://ncbi.nlm.nih.gov/pubmed/21931275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.10.16600 |
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