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Substrate and product specificities of SET domain methyltransferases

SET domain lysine methyltransferases (KMTs) catalyze the site- and state-specific methylation of lysine residues in histone and non-histone substrates. These modifications play fundamental roles in transcriptional regulation, heterochromatin formation, X chromosome inactivation and DNA damage respon...

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Autors principals: Del Rizzo, Paul A, Trievel, Raymond C
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225744/
https://ncbi.nlm.nih.gov/pubmed/21847010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.9.16069
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