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Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases

Molecular dynamics and hybrid quantum mechanics/molecular mechanics have been used to investigate the mechanisms of (+)AdoMet methylation of protein-Lys-NH(2) catalyzed by the lysine methyltransferase enzymes: histone lysine monomethyltransferase SET7/9, Rubisco large-subunit dimethyltransferase, vi...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaodong, Bruice, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311330/
https://ncbi.nlm.nih.gov/pubmed/18391193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801788105
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