Excessive erythrocytosis compromises the blood–endothelium interface in erythropoietin-overexpressing mice

ABSTRACT: Elevated systemic haematocrit (Hct) increases risk of cardiovascular disorders, such as stroke and myocardial infarction. One possible pathophysiological mechanism could be a disturbance of the blood–endothelium interface. It has been shown that blood interacts with the endothelial surface...

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Detalhes bibliográficos
Main Authors: Richter, Vincent, Savery, Michele D, Gassmann, Max, Baum, Oliver, Damiano, Edward R, Pries, Axel R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225673/
https://ncbi.nlm.nih.gov/pubmed/21859826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.209262
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