T-cell Acute Leukemia 1 (TAL1) Regulation of Erythropoietin Receptor and Association with Excessive Erythrocytosis

During erythropoiesis, erythropoietin stimulates induction of erythroid transcription factors that activate expression of erythroid genes including the erythropoietin receptor (EPO-R) that results in increased sensitivity to erythropoietin. DNA binding of the basic helix-loop-helix transcription fac...

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Detalhes bibliográficos
Main Authors: Rogers, Heather, Wang, Li, Yu, Xiaobing, Alnaeeli, Mawadda, Cui, Kairong, Zhao, Keji, Bieker, James J., Prchal, Josef, Huang, Suming, Weksler, Babette, Noguchi, Constance Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481276/
https://ncbi.nlm.nih.gov/pubmed/22982397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378398
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