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Role of PDE3A in Regulation of Cell Cycle Progression in Mouse Vascular Smooth Muscle Cells and Oocytes: Implications in Cardiovascular Diseases and Infertility

Phosphodiesterase-3 (PDE3) is a major cAMP-hydrolyzing PDE in vascular smooth muscle cells (VSMCs) and oocytes. The exact role and contribution of the two PDE3 isoforms, PDE3A and PDE3B, in VSMC growth regulation and oocyte maturation was examined using PDE3A (3A) and PDE3B (3B) knockout (KO) mouse...

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Bibliografische gegevens
Hoofdauteurs: Begum, Najma, Shen, Weixing, Manganiello, Vincent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225595/
https://ncbi.nlm.nih.gov/pubmed/22051884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.10.006
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