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Brimonidine Tartrate–Eudragit Long-Acting Nanoparticles: Formulation, Optimization, In Vitro and In Vivo Evaluation

In the present study, an effort was made to design prolonged release Eudragit nanoparticles of brimonidine tartrate by double emulsion–solvent evaporation technique for the treatment of open-angle glaucoma. The effect of various formulation variables like initial drug amount, lecithin proportion, ph...

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Detalhes bibliográficos
Main Authors: Bhagav, Prakash, Upadhyay, Hariom, Chandran, Sajeev
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225524/
https://ncbi.nlm.nih.gov/pubmed/21879393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9675-1
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