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Floating Elementary Osmotic Pump Tablet (FEOPT) for Controlled Delivery of Diethylcarbamazine Citrate: a Water-Soluble Drug

The present work investigates the feasibility of the design of a novel floating elementary osmotic pump tablet (FEOPT) to prolong the gastric residence of a highly water-soluble drug. Diethylcarbamazine citrate (DEC) was chosen as a model drug. The FEOPT consisted of an osmotic core (DEC, mannitol,...

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Détails bibliographiques
Auteurs principaux: Khan, Zulfequar Ahamad, Tripathi, Rahul, Mishra, Brahmeshwar
Format: Artigo
Langue:Inglês
Publié: Springer US 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225518/
https://ncbi.nlm.nih.gov/pubmed/21969244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9699-6
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