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A Conserved Antioxidant Response Element (ARE) in the Promoter of Human Carbonyl Reductase 3 (CBR3) Mediates Induction by the Master Redox Switch Nrf2

Carbonyl reductase activity catalyzes the two electron reduction of several endogenous and exogenous carbonyl substrates. Recent data indicate that the expression of human carbonyl reductase 3 (CBR3) is regulated by the master redox switch Nrf2. Nrf2 binds to conserved antioxidant response elements...

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Main Authors: Cheng, Qiuying, Kalabus, James L., Zhang, Jianping, Blanco, Javier G.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225504/
https://ncbi.nlm.nih.gov/pubmed/22001310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.09.027
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