Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemia

Blood of patients with sickle cell anemia (SS) exhibits decreased affinity for oxygen, although the oxygen affinity of hemoglobin S is the same as that of hemoglobin A. SS red cells contain more 2,3-diphosphoglycerate (DPG) than normal erythrocytes. The oxygen affinity of hemolyzed red cells is decr...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Charache, Samuel, Grisolia, Santiago, Fiedler, Adam J., Hellegers, Andre E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1970
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5443181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106294
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