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Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemia

Blood of patients with sickle cell anemia (SS) exhibits decreased affinity for oxygen, although the oxygen affinity of hemoglobin S is the same as that of hemoglobin A. SS red cells contain more 2,3-diphosphoglycerate (DPG) than normal erythrocytes. The oxygen affinity of hemolyzed red cells is decr...

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Detalhes bibliográficos
Main Authors: Charache, Samuel, Grisolia, Santiago, Fiedler, Adam J., Hellegers, Andre E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC322537/
https://ncbi.nlm.nih.gov/pubmed/5443181
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