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Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it

Mycobacterium tuberculosis is a facultative intracellular pathogen that parasitizes host macrophages where it persists in immature phagosomes by avoiding their maturation into phagolysosomes. The mechanisms of how M. tuberculosis inhibits phagolysosome biogenesis have been researched in detail and t...

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Détails bibliographiques
Auteur principal: Deretic, Vojo
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225291/
https://ncbi.nlm.nih.gov/pubmed/18811236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/17460913.3.5.517
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