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Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity of Mammalian Proteomes

The ability to sequence genomes has far outstripped approaches for deciphering the information they encode. Here we present a suite of techniques, based on ribosome profiling (the deep-sequencing of ribosome-protected mRNA fragments), to provide genome-wide maps of protein synthesis as well as a pul...

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Hlavní autoři: Ingolia, Nicholas T., Lareau, Liana F., Weissman, Jonathan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225288/
https://ncbi.nlm.nih.gov/pubmed/22056041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.002
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