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Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells

BACKGROUND: Open reading frames are common in long noncoding RNAs (lncRNAs) and 5’UTRs of protein coding transcripts (uORFs). The question of whether those ORFs are translated was recently addressed by several groups using ribosome profiling. Most of those studies concluded that certain lncRNAs and...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Popa, Alexandra, Lebrigand, Kevin, Barbry, Pascal, Waldmann, Rainer
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712605/
https://ncbi.nlm.nih.gov/pubmed/26764022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2384-0
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