Unique Characteristics of AAV1, 2, and 5 Viral Entry, Intracellular Trafficking, and Nuclear Import Define Transduction Efficiency in HeLa Cells

Biological differences between recombinant adeno-associated virus (rAAV) serotypes define their efficiencies in expressing a transgene in a particular target cell. Few studies have directly compared how differences in viral entry, intracellular trafficking, and nuclear import of rAAV serotypes influ...

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Bibliographic Details
Main Authors: Keiser, Nicholas W., Yan, Ziying, Zhang, Yulong, Lei-Butters, Diana C.M., Engelhardt, John F.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225038/
https://ncbi.nlm.nih.gov/pubmed/21574868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.044
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