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Retinal transfer of nicotinate by H(+)-monocarboxylate transporter at the inner blood-retinal barrier

Nicotinic acid is a constituent of the coenzymes NAD and NADP. It also serves as an agonist for the G-protein-coupled receptor GPR109A. Nicotinic acid is widely used at high doses as a lipid-lowering drug, which is associated with an ocular side effect known as niacin maculopathy. Here we investigat...

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Hlavní autoři: Tachikawa, Masanori, Murakami, Koji, Martin, Pamela, Hosoya, Ken-ichi, Ganapathy, Vadivel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225029/
https://ncbi.nlm.nih.gov/pubmed/21741392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2011.06.009
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