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In the clinic: ongoing clinical trials evaluating c-MET-inhibiting drugs

The c-MET (mesenchymal–epithelial transition factor) pathway is dysregulated in many human cancers and promotes tumor growth, invasion and dissemination. The c-MET receptor tyrosine kinase can be activated via gene mutation, gene amplification, protein overexpression and/or a ligand-dependent autocr...

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Detalhes bibliográficos
Main Authors: Sharma, Neelesh, Adjei, Alex A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225020/
https://ncbi.nlm.nih.gov/pubmed/22128287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834011423403
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