A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C)

Tyrosine kinase 2 (Tyk2) is an integral part of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway which relays intracellular signals of various cytokines. Tyk2 crucially contributes to host defense mechanisms against microbial pathogens and to tumor surveillance bu...

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Main Authors: Grunert, Tom, Leitner, Nicole R., Marchetti-Deschmann, Martina, Miller, Ingrid, Wallner, Barbara, Radwan, Marta, Vogl, Claus, Kolbe, Thomas, Kratky, Dagmar, Gemeiner, Manfred, Allmaier, Günter, Müller, Mathias, Strobl, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225013/
https://ncbi.nlm.nih.gov/pubmed/21787891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.07.006
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