Distinct mechanisms regulate GABA(A) receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells

ABSTRACT: Pyramidal cells express various GABA(A) receptor (GABA(A)R) subtypes, possibly to match inputs from functionally distinct interneurons targeting specific subcellular domains. Postsynaptic anchoring of GABA(A)Rs is ensured by a complex interplay between the scaffolding protein gephyrin, neu...

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Detalhes bibliográficos
Main Authors: Panzanelli, Patrizia, Gunn, Benjamin G, Schlatter, Monika C, Benke, Dietmar, Tyagarajan, Shiva K, Scheiffele, Peter, Belelli, Delia, Lambert, Jeremy J, Rudolph, Uwe, Fritschy, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Neuroscience: Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224886/
https://ncbi.nlm.nih.gov/pubmed/21825022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.216028
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