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Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps

BACKGROUND: Peptide Recognition Domains (PRDs) are commonly found in signaling proteins. They mediate protein-protein interactions by recognizing and binding short motifs in their ligands. Although a great deal is known about PRDs and their interactions, prediction of PRD specificities remains large...

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Bibliografiska uppgifter
Huvudupphovsmän: Yip, Kevin Y, Utz, Lukas, Sitwell, Simon, Hu, Xihao, Sidhu, Sachdev S, Turk, Benjamin E, Gerstein, Mark, Kim, Philip M
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224579/
https://ncbi.nlm.nih.gov/pubmed/21835011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-53
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