A model-based circular binary segmentation algorithm for the analysis of array CGH data

BACKGROUND: Circular Binary Segmentation (CBS) is a permutation-based algorithm for array Comparative Genomic Hybridization (aCGH) data analysis. CBS accurately segments data by detecting change-points using a maximal-t test; but extensive computational burden is involved for evaluating the signific...

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Main Authors: Hsu, Fang-Han, Chen, Hung-I H, Tsai, Mong-Hsun, Lai, Liang-Chuan, Huang, Chi-Cheng, Tu, Shih-Hsin, Chuang, Eric Y, Chen, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224564/
https://ncbi.nlm.nih.gov/pubmed/21985277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-394
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