The hypoxia-responsive lncRNA NDRG-OT1 promotes NDRG1 degradation via ubiquitin-mediated proteolysis in breast cancer cells

Hypoxia can lead to solid tumor aggressiveness by driving multiple signaling pathways. Long non-coding RNAs respond to several extrinsic stimuli, causing changes in cancer cells by participating in multiple steps of gene expression. However, genomic profiling of long non-coding RNAs regulated by oxy...

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Publicat a:Oncotarget
Autors principals: Lin, Hsin-Chen, Yeh, Ching-Ching, Chao, Lo-Yun, Tsai, Mong-Hsun, Chen, Hung-Hsin, Chuang, Eric Y., Lai, Liang-Chuan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828211/
https://ncbi.nlm.nih.gov/pubmed/29535820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23732
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