The PACOVAR-trial: A phase I/II study of pazopanib (GW786034) and cyclophosphamide in patients with platinum-resistant recurrent, pre-treated ovarian cancer

BACKGROUND: The prognosis of patients with recurrent, platinum-resistant epithelial ovarian cancer (EOC) is poor. There is no standard treatment available. Emerging evidence suggests a major role for antiangiogenic treatment modalities in EOC, in particular in combination with the metronomic applica...

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Hlavní autoři: Eichbaum, Michael, Mayer, Christine, Eickhoff, Regina, Bischofs, Esther, Gebauer, Gerhard, Fehm, Tanja, Lenz, Florian, Fricke, Hans-Christian, Solomayer, Erich, Fersis, Nikos, Schmidt, Marcus, Wallwiener, Markus, Schneeweiss, Andreas, Sohn, Christof
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224456/
https://ncbi.nlm.nih.gov/pubmed/22014006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-453
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