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Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells

Fenfluramine is prescribed either alone or in combination with phentermine as part of Fen-Phen, an anti-obesity medication. Fenfluramine was withdrawn from the US market in 1997 due to reports of heart valvular disease, pulmonary arterial hypertension, and cardiac fibrosis. Particularly, idiopathic...

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Main Authors: Yao, Weijuan, Mu, Wenbo, Zeifman, Amy, Lofti, Michelle, Remillard, Carmelle V., Makino, Ayako, Perkins, David L., Garcia, Joe G., Yuan, Jason X. J., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224433/
https://ncbi.nlm.nih.gov/pubmed/22140631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.87310
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