Coactivation of TLR4 and TLR2/6 Coordinates an Additive Augmentation on IL-6 Gene Transcription via p38 MAPK Pathway in U937 Mononuclear Cells

Studies have demonstrated that TLR4 and TLR2 expression by monocytes and the blood levels of TLR4 and TLR2 ligand in diabetic patients are significantly incased compared to nondiabetic patients, indicating that more monocytes in diabetic patients may have coactivation of TLR4 and TLR2. Although it h...

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Hlavní autoři: Jin, Junfei, Samuvel, Devadoss J., Zhang, Xiaoming, Li, Yanchun, Lu, Zhongyang, Lopes-Virella, Maria F., Huang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224151/
https://ncbi.nlm.nih.gov/pubmed/22030478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.08.026
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