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IL-6 and High Glucose Synergistically Upregulate MMP-1 Expression by U937 Mononuclear Phagocytes via ERK1/2 and JNK Pathways and c-Jun
Matrix metalloproteinases (MMPs) play a pivotal role in tissue remodeling and destruction in inflammation-associated diseases such as cardiovascular disease and periodontal disease. Although it is known that interleukin (IL)-6 is a key proinflamatory cytokine, it remains unclear how IL-6 regulates M...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858773/ https://ncbi.nlm.nih.gov/pubmed/20225236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22532 |
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