Detection of methylation in the CpG islands of the p16INK4A, RASSF 1A and methylguanine methyltransferase gene promoters in pancreatic adenocarcinoma

Pancreatic cancer consists of an accumulation of genetic and epigenetic alterations. Recently, aberrant methylation of CpG islands of cancer-related genes has emerged as an important epigenetic mechanism of their transcriptional dysregulation during tumour development [1]. Therefore, new diagnostic...

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Detalhes bibliográficos
Main Authors: Paikos, D, Stravoravdi, P, Voyatzi, S, Boukovinas, I, Papakotoulas, P, Kiziridou, A, Sibilidis, G, Stergiou, I
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2009
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223988/
https://ncbi.nlm.nih.gov/pubmed/22276000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2009.131
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