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Cleavage of Multiple Disulfide Bonds in Insulin via Gold Cationization and Collision-induced Dissociation
Intact bovine insulin, with its two chains linked via two disulfide linkages, has been used as a model system to study the incorporation of one or more gold cations as means for facilitating the cleavage of multiple disulfide bonds in a tandem mass spectrometry experiment. Gas-phase ion/ion reaction...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223978/ https://ncbi.nlm.nih.gov/pubmed/22125416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2011.08.013 |
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