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Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice

Diarrheal diseases represent a major health burden in developing countries. Parenteral immunization typically does not induce efficient protection against enteropathogens because it does not stimulate migration of immune cells to the gut. Retinoic acid (RA) is critical for gut immunity, inducing upr...

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Detalhes bibliográficos
Main Authors: Hammerschmidt, Swantje I., Friedrichsen, Michaela, Boelter, Jasmin, Lyszkiewicz, Marcin, Kremmer, Elisabeth, Pabst, Oliver, Förster, Reinhold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223921/
https://ncbi.nlm.nih.gov/pubmed/21737878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44262
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